The Laboratory of Applied Microbiology (LMA) was founded as part of the Cantonal Institute of Microbiology (ICM), established in 1964 to fill a gap in health care for the population of Canton Ticino. Over the years, the activities related to public mandates, teaching and research have gained importance. To maintain and develop the expertise in microbiology necessary for applied research in Southern Switzerland, LMA was integrated into SUPSI in January 2014. LMA is nowadays a reference point for applied microbiology for SUPSI, the Canton and the region.